We live in challenging times with a heightened sense of uncertainty and unpredictability. Climate change, with its creation of disruptive events as well as gradual trends, has been addressed in scientific studies and become increasingly important in policymaking. This presents a great need for scientific integration and knowledge transformation. The Taiwan Integrated Research Programme on Climate Change Adaptation Technology (TaiCCAT) is formed under this concern. Directed by the Ministry of Science and Technology (MOST), it carries the strong intention to explore and conduct adequate knowledge of climate change and adaptation strategies for decision-making support. The TaiCCAT highly recommends the cross-disciplinary collaboration approach from environmental studies to adaptation governance. The resultswould therefore better reflect the complexity of the changing world.