New spectrophotometric CCD-observations of Saturn were performed in 2003 - 2004 within the framework of an international effort in support to the Cassini space mission through 2008. A series of Saturn¡¦s spectra have been obtained and analyzed. Our purpose is to study current latitudinal variations in molecular absorption bands during the rings-opening maximum and best visibility conditions for observation of the southern hemisphere of Saturn. A comparison with data of previous years shows the presence of seasonal variation connected with changes in the insolation regime on Saturn.